Effects of endotracheal suctioning in high-frequency oscillatory and conventionally ventilated low birth weight neonates on cerebral hemodynamics observed by near infrared spectroscopy (NIRS)

2000 ◽  
Vol 29 (4) ◽  
pp. 270-275 ◽  
Author(s):  
C. Kohlhauser ◽  
G. Bernert ◽  
M. Hermon ◽  
C. Popow ◽  
R. Seidl ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Near Infrared Spectroscopy ◽  
High Frequency ◽  
Near Infrared ◽  
Cerebral Hemodynamics ◽  
Endotracheal Suctioning ◽  
High Frequency Oscillatory

scholarly journals Application of near-infrared spectroscopy in extremely and very low birth weight infants for red blood cells transfusion

2020 ◽  
Vol 19 (3) ◽  
pp. 18-25
Author(s):  
D. R. Sharafutdinova ◽  
E. N. Balashova ◽  
O. V. Ionov ◽  
A. R. Kirtbaya ◽  
J. M. Golubtsova ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Red Blood Cells ◽  
Near Infrared Spectroscopy ◽  
Blood Cells ◽  
Near Infrared ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Non Invasive

Near-infrared spectroscopy (NIRS), or cerebral oximetry, is a non-invasive method for assessing the oxidative status (saturation of hemoglobin with oxygen) mainly in the blood of cerebral venous vessels, which is increasingly used in clinical practice, in particular in neonatology. This method allows us to evaluate not only tissue perfusion, but also to determine the differences between the indicators of cerebral and peripheral oxygenation. Few studies have described improvements in tissue oxygenation indicators determined by NIRS after red blood cells transfusion in premature newborns. In our study we registered the oximetry indicators before and after red blood cells transfusion in extremely and very low birth weight infants (n = 55). This clinical study was approved by the Biomedical Research Ethics Committee (Protocol No. 19 dated 17 November 2016) and the Scientific Council of the Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of Ministry of Healthcare of the Russian Federation (Protocol No. 19 dated 29 November 2016). Our study demonstrated a statistically significant increase in CrSO2 , SrSO2 , RrSO2 and SCOR and a decrease in C-FTOE, S-FTOE after a blood transfusion. The study also showed that a decrease in NIRS values (SCOR ≤ 0.76, C-FTOE ≥ 0.29, CrSO2 ≤ 64%, SrSO2 ≤ 54%, and RrSO2 ≤ 56%) can serve as an additional non-invasive measure of anemia and its progression; it helps detect a decrease in cerebral oxygenation at an early, preclinical stage of disease, and can also be used as an additional indicator of the need for red blood cell transfusions. 

Near-Infrared Spectroscopy Monitoring, Superior Vena Cava Flow, and Neurodevelopmental Outcome at 2 years in a Cohort of Very Low-Birth-Weight Infants

2016 ◽  
Vol 33 (11) ◽  
pp. 1093-1098 ◽  
Author(s):  
Rosa Cerbo ◽  
Simona Orcesi ◽  
Luigia Scudeller ◽  
Martina Borellini ◽  
Carolina Croci ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Very Low Birth Weight ◽  
Superior Vena ◽  
Neurodevelopmental Outcome ◽  
Vena Cava ◽  
Low Birth Weight Infants

Objective We aimed at assessing the association between superior vena cava flow (SVCf), regional (cerebral) tissue oxygen saturation (rSO2), and cerebral fractional oxygen extraction (CFOE) during the first 48 hours of life and 2-years neurodevelopmental outcome of very low-birth-weight infants (VLBW). Methods We prospectively studied 60 VLBW infants admitted to our neonatal intensive care unit; rSO2 was continuously monitored with near-infrared spectroscopy during the first 48 hours of life, SVCf was measured at 4 to 6, 12, 24, and 48 hours, and CFOE was calculated. Neurodevelopmental outcome was assessed at 24 months corrected age. Results The mean gestational age at birth was 27.9 weeks (standard deviation: 2.4); 8 infants died in the first 3 months of life, 6 were lost to follow-up, 46 survived and were followed up. At 24 months, 6 (13%) and 7 (15.2%) infants developed minor and major sequelae, respectively. Infants who died had higher CFOE (p < 0.001) and lower SVCf (p < 0.001) than infants surviving with sequelae. In turn, these had higher SVCf between 24 and 48 hours than those without sequelae (p < 0.001). Conclusion SVCf, rSO2, and CFOE patterns in the first days of life suggest cerebral hyperperfusion, related to loss of autoregulation and/or use of inotropic drugs, as a potential mechanism of cerebral injury.

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